Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased expression of Hsp70 for resistance to deuterium oxide in a yeast mutant cell line.

Biological & pharmaceutical bulletin - 1 Jun 2003

Unno Keiko, Kishido Takahiro, Morioka Mizue, Okada Shoji, Oku Naoto

Abstract excerpt

Labeling with stable isotopes, typically deuterium (D), is powerful tool for studying the functional structure of biomolecules by NMR. Biosynthesis of certain deuterated proteins in microorganisms cultured in deuterium oxide (D(2)O) is an attractive strategy. However, the growth of almost all microorganisms is inhibited at high concentrations of D(2)O. We isolated a mutant of yeast that grows well in D(2)O. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cold Temperature
Share to Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HSP70 Heat-Shock Proteins

Share to Isotope Labeling

Share to Nuclear Magnetic Resonance, Biomolecular

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 12808289
DOI: 10.1248/bpb.26.799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased expression of Hsp70 for resistance to deuterium oxide in a yeast mutant cell line.PMID 12808289Read ↗

Enhancing protein perdeuteration by experimental evolution of Escherichia coli K-12 for rapid growth in deuterium-based media.Semantic proximity Read ↗

Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water.Semantic proximity Read ↗

2nSILAC for Quantitative Proteomics of Prototrophic Baker's Yeast.Semantic proximity Read ↗

Evolving Escherichia coli Host Strains for Efficient Deuterium Labeling of Recombinant Proteins Using Sodium Pyruvate-d3.Semantic proximity Read ↗

A new simple method for isolating multistress-tolerant semidominant mutants of Saccharomyces cerevisiae by one-step selection under lethal hydrogen peroxide stress condition.Semantic proximity Read ↗

Isolation of baker's yeast mutants with proline accumulation that showed enhanced tolerance to baking-associated stresses.Semantic proximity Read ↗

Isolation and characterization of baker's yeast capable of strongly activating a macrophage.Semantic proximity Read ↗

A highly thermosensitive and permeable mutant of the marine yeast Cryptococcus aureus G7a potentially useful for single-cell protein production and its nutritive components.Semantic proximity Read ↗

The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiae.Semantic proximity Read ↗

Isolation and characterization of awamori yeast mutants with L-leucine accumulation that overproduce isoamyl alcohol.Semantic proximity Read ↗

Heat protection by deuterium oxide of heat sensitive and wild-type Chinese hamster ovary cells.Semantic proximity Read ↗

Temperature-sensitive mutants of hsp82 of the budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.