Article
Evaluation of the epidemiologic utility of secondary typing methods for differentiation of Mycobacterium tuberculosis isolates.
Journal of clinical microbiology - 1 Jun 2003
Kwara Awewura, Schiro Ronald, Cowan Lauren S, Hyslop Newton E, Wiser Mark F, Roahen Harrison Stephanie, Kissinger Patricia, Diem Lois, Crawford Jack T
Abstract excerpt
Spoligotyping and mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis (MIRU-VNTR) were evaluated for the ability to differentiate 64 Mycobacterium tuberculosis isolates from 10 IS6110-defined clusters. MIRU-VNTR performed slightly better than spoligotyping in reducing the number of clustered isolates and the sizes of the clusters. All epidemiologically related isolates remained...
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