Article
Melanoma etiology: where are we?
Oncogene - 19 May 2003
Tucker Margaret A, Goldstein Alisa M
Abstract excerpt
Melanoma incidence rates are rising rapidly, particularly in older men. Older men are also more likely to have thick melanomas, which confer high mortality and morbidity. The reasons for the rate of increase are not known; increasing sun and UV exposure, however, is the major hypothesized explanation. In the past several years, two major susceptibility genes for melanoma, CDKN2A and CDK4, have been identified,...
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