Article
The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation.
The Journal of clinical endocrinology and metabolism - 1 Jun 2003
Gurnell Mark, Savage David B, Chatterjee V Krishna K, O'Rahilly Stephen
Abstract excerpt
By the end of this decade, it has been estimated that between 200 million and 300 million people worldwide will meet World Health Organization diagnostic criteria for diabetes mellitus. This epidemic of predominantly type 2 diabetes has largely been mediated by our shift toward a more sedentary lifestyle predisposing to obesity and insulin resistance. Affected individuals can also exhibit an array of associated...
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