Article
Prevalence and molecular diversity of pHS-2 plasmids, marker for arthritogenicity, among clinical Escherichia coli Shigella isolates.
Microbes and infection - 1 Jun 2003
Adam Thomas, Siewerdt Roland, Offermann Indre, Lang Jörg, Tschäpe Helmut, Sieper Joachim, Graf Barbara
Abstract excerpt
Reactive arthritis can occur after numerous bacterial infections, including bacillary dysentery caused by Escherichia coli Shigella. A major risk factor for the disease is the HLA B27 phenotype in the human host. By comparison between plasmid profiles of arthritogenic vs. nonarthritogenic Shigella strains, the pHS-2 plasmid has been previously associated with the arthritogenic capacity of Shigella isolates....
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