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Article

Genetic background influences cataractogenesis, but not lens growth deficiency, in Cx50-knockout mice.

Investigative ophthalmology & visual science - 1 Jun 2003

Gerido Dwan A, Sellitto Caterina, Li Leping, White Thomas W

Abstract excerpt

PURPOSE: Deletion of connexin (Cx)50 produces microphthalmia with nuclear cataracts. To determine whether these two traits are influenced by genetic background and are dependent on each other, mice carrying the Cx50 deletion in two different strains were generated, and the growth defect and sever...

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Share to Cataract
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crystallins

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Share to Mice, Knockout

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Source

Identifiers

PMID: 12766071
DOI: 10.1167/iovs.02-1311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12766071-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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