Article
Evidence of apoptosis via TUNEL staining in muscle biopsy from patients with mitochondrial encephaloneuromyopathies.
Journal of submicroscopic cytology and pathology - 1 Jan 2003
Formichi P, Battisti C, Bianchi S, Cardaioli E, Federico A
Abstract excerpt
Apoptosis is an evolution-conserved form of cell death essential for development and maintenance of tissue homeostasis. Dysregulation of apoptosis has been implicated in several pathological conditions, including neurodegenerative disorders. The crucial role of mitochondria in regulation of the apoptotic pathway prompted us to investigate the pattern of apoptosis in muscle biopsies from 17 patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
