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Article

Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae.

European journal of biochemistry - 1 Jun 2003

Gueldry Olivier, Lazard Myriam, Delort Florence, Dauplais Marc, Grigoras Ioana, Blanquet Sylvain, Plateau Pierre

Abstract excerpt

In Saccharomyces cerevisiae, disruption of the YCF1 gene increases the sensitivity of cell growth to mercury. Transformation of the resulting ycf1 null mutant with a plasmid harbouring YCF1 under the control of the GAL promoter largely restores the wild-type resistance to the metal ion. The protective effect of Ycf1p against the toxicity of mercury is especially pronounced when yeast cells are grown in rich...

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Share to ATP-Binding Cassette Transporters
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12755704
DOI: 10.1046/j.1432-1033.2003.03620.x

Genes

GAL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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