Article
Characterization of Staphylococcus aureus Strains Isolated from Czech Cystic Fibrosis Patients: High Rate of Ribosomal Mutation Conferring Resistance to MLS(B) Antibiotics as a Result of Long-Term and Low-Dose Azithromycin Treatment.
Microbial drug resistance (Larchmont, N.Y.) - 1 Aug 2015
Tkadlec Jan, Vařeková Eva, Pantůček Roman, Doškař Jiří, Růžičková Vladislava, Botka Tibor, Fila Libor, Melter Oto
Abstract excerpt
Staphylococcus aureus is one of the most frequent pathogens infecting the respiratory tract of patients with cystic fibrosis (CF). This study was the first to examine S. aureus isolates from CF patients in the Czech Republic. Among 100 S. aureus isolates from 92 of 107 observed patients, we found a high prevalence of resistance to macrolide-lincosamide-streptogramin B (MLS(B)) antibiotics (56%). More than half of...
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