Article
p38 Mitogen-activated protein kinase regulation of JB6 Cl41 cell transformation promoted by epidermal growth factor.
The Journal of biological chemistry - 18 Jul 2003
He Zhiwei, Cho Yong-Yeon, Liu Guangming, Ma Wei-Ya, Bode Ann M, Dong Zigang
Abstract excerpt
The relationship between cell transformation and p38 MAP kinase, a major mitogen-activated protein (MAP) kinase pathway converting signals of various extracellular stimuli into expression of specific target genes through activation of transcription factors, still remains unclear. The aim of the present study was to investigate the role of the p38 MAP kinase pathway in epidermal growth factor (EGF)-induced cell...
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