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Article

Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis.

Clinical chemistry and laboratory medicine - 1 Apr 2003

Harrington Dominic J, Malefora Agata, Schmeleva Veronika, Kapustin Sergey, Papayan Ludmila, Blinov Mikhail, Harrington Pip, Mitchell Mike, Savidge Geoffrey F

Abstract excerpt

We undertook genetic and biochemical assays in patients with arterial (n = 146) and venous (n = 199) thromboembolism and survivors of pulmonary embolism (n = 58) to study causation and gene-life style interactions. In the clinical material from North Western Russia, factor V Leiden was found to be a risk factor in venous thrombosis (OR = 3.6), while the methylenetetrahydrofolate reductase (MTHFR) C677T mutation...

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Identifiers

PMID: 12747593
DOI: 10.1515/CCLM.2003.075

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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