Article
Angiotensinogen polymorphisms and elevated blood pressure in the general population: the Copenhagen City Heart Study.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2001
Sethi A A, Nordestgaard B G, Agerholm-Larsen B, Frandsen E, Jensen G, Tybjaerg-Hansen A
Abstract excerpt
In the present study, we tested the hypothesis that the Met235Thr and Thr174Met mutations were associated or not with elevated blood pressure. We genotyped 9100 women and men from the Danish general population, of whom 54% had elevated blood pressure. Of the 9100, 41% and 12% carried the Thr235 and Met174 mutations, respectively; the Met174 mutation always occurred on the same allele as the Thr235 mutation. On...
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