Article
Toxicogenetics: applications and opportunities.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Sept 2003
Orphanides George, Kimber Ian
Abstract excerpt
The response to drugs and environmental chemicals varies with genotype. Some patients react well to drugs, while others may not benefit, or may even respond adversely. Individuals also experience different reactions to environmental agents, such as allergens. The sequencing of the human genome and the large-scale identification of genome polymorphisms have provided opportunities for understanding the genetic...
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