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Article

RNase H overproduction allows the expression of stress-induced genes in the absence of topoisomerase I.

FEMS microbiology letters - 25 Apr 2003

Cheng Bokun, Rui Shan, Ji Chengling, Gong Vivien W, Van Dyk Tina K, Drolet Marc, Tse-Dinh Yuk-Ching

Abstract excerpt

Induction of stress proteins in response to heat shock was found to be reduced significantly in Escherichia coli with DeltatopA mutation. RNase H overexpression in the DeltatopA mutant partially restored the sigma(32)-dependent induction of stress genes in response to high temperature and ethanol. The presence of overexpressed RNase H also improved the survival rate of the DeltatopA mutant after high temperature...

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Share to DNA, Bacterial
Share to DNA Topoisomerases, Type I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

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Share to Nucleic Acid Conformation

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Source

Identifiers

PMID: 12725933
DOI: 10.1016/S0378-1097(03)00209-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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