[Genetic defects as markers of tumor development].

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Article

[Genetic defects as markers of tumor development].

Molekuliarnaia biologiia - 1 Jan 2000

Likhtenshteĭn A V, Potapova G I

Abstract excerpt

Carcinogenesis is long-term multistep accumulation of defects of genes responsible for cell division, DNA repair, and apoptosis. The functions of these genes are known both for norm and for pathologies caused by their damage and resulting in "asocial" cell behavior. Owing to the recent progress in studying the mechanisms of carcinogenesis, some genetic defects may be considered from the applied point of view (as...

Topics

Aging
Apoptosis
Biomarkers, Tumor
DNA, Neoplasm
Genes, Tumor Suppressor
Humans
Mutation
Neoplasms
Oncogenes
Proteins

Source

Open in PubMed

Identifiers

PMID: 12723466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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