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Pleiotropic effect due to targeted depletion of secretory rhoptry protein ROP2 inToxoplasma gondii

1 May 2003

Abstract excerpt

Long after their discovery, the function and biogenesis of rhoptries remain enigmatic. In Apicomplexan parasites, these organelles discharge and their contents are exocytosed at the time of host cell invasion, and are thus proposed to play an essential role in establishing the parasitophorous vacuole. In Toxoplasma gondii, ROP2 is suspected to serve as the molecular link between host cell mitochondria and...

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PMID: 12711703
DOI: 10.1242/jcs.00382

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