Article
Acceptable age for prophylactic surgery in children with multiple endocrine neoplasia type 2a.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 May 2003
Kahraman T, de Groot J W B, Rouwe C, Hofstra R M W, Links Th P, Sijmons R H, Plukker J Th M
Abstract excerpt
AIMS: Germline mutated RET proto-oncogene, causing multiple endocrine neoplasia (MEN)-2a syndrome is the indication for prophylactic total thyroidectomy. Literature regarding the risk and the extent of early surgical intervention is scarce and the optimum age for surgery is still controversial. To optimize management in these young children we evaluate our experience and results. PATIENTS AND METHODS: From 1990...
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