Article
A genomewide screen for generalized vitiligo: confirmation of AIS1 on chromosome 1p31 and evidence for additional susceptibility loci.
American journal of human genetics - 1 Jun 2003
Fain Pamela R, Gowan Katherine, LaBerge Greggory S, Alkhateeb Asem, Stetler Gary L, Talbert Janet, Bennett Dorothy C, Spritz Richard A
Abstract excerpt
Generalized vitiligo is a common autoimmune disorder characterized by the development of white patches of skin and overlying hair due to loss of pigment-forming melanocytes from the involved areas. Family clustering of cases is not uncommon, in a pattern suggestive of multifactorial, polygenic inheritance, and there is strong association between vitiligo and other autoimmune diseases. To map genetic loci that...
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