Article
Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2.
Human molecular genetics - 15 Mar 2002
Alkhateeb Asem, Stetler Gary L, Old William, Talbert Janet, Uhlhorn Cynthia, Taylor Melanie, Fox Angela, Miller Cynthia, Dills Diana G, Ridgway E Chester, Bennett Dorothy C, Fain Pamela R, Spritz Richard A
Abstract excerpt
Generalized vitiligo is a common autoimmune disorder in which patchy loss of skin and hair pigmentation results from loss of pigment-forming melanocytes from the involved regions. Vitiligo occurs with a frequency of about 1% in most populations, and is highly associated with other autoimmune disorders, particularly Hashimoto thyroiditis. Most cases of vitiligo are sporadic, although some cases cluster in...
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