Article
Phenotypic differentiation of human breast cancer cells by 1,3 cyclic propanediol phosphate.
Cancer letters - 8 May 2003
Adan Yosef, Goldman Yechiel, Haimovitz Rachel, Mammon Keren, Eilon Tali, Tal Saar, Tene Anat, Karmel Yael, Shinitzky Meir
Abstract excerpt
Breast cancer cells in their virulent undifferentiated state are characterized by lack of functional estrogen receptors (ER) and/or progesterone receptors (PR) as well as relatively low levels of other normal differentiation markers such as milk proteins and lipid droplets. To date, no method for in situ elevation of the state of differentiation of breast cancer cells has yet been proven effective in patients. We...
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