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Article

Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-C(deltaNdeltaC)- and VEGF-A-induced angiogenesis in vitro.

Experimental cell research - 1 May 2003

Tille Jean-Christophe, Wang Xueyan, Lipson Kenneth E, McMahon Gerald, Ferrara Napoleone, Zhu Zhenping, Hicklin Daniel J, Sleeman Jonathan P, Eriksson Ulf, Alitalo Kari, Pepper Michael S

Abstract excerpt

Angiogenesis and lymphangiogenesis are regulated by members of the vascular endothelial growth factor (VEGF) family of cytokines, which mediate their effects via tyrosine kinase VEGF receptors -1, -2, and -3. We have used wild-type and mutant forms of VEGFs -A, -B, and -C, a pan-VEGFR tyrosine kinase inhibitor (SU5416) as well as neutralizing anti-VEGFR-2 antibodies, to determine which VEGF receptor(s) are...

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Identifiers

PMID: 12706123
DOI: 10.1016/s0014-4827(03)00053-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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