Regression methods for assessing familial aggregation of disease.

Abstract excerpt

This paper reviews methods for assessing familial aggregation of disease based on simple logistic regression models. Studies are based on a case-control sampling design, where the disease status of the first degree relatives of both cases and controls are obtained. Both 'proband predictive' and 'family predictive' models are discussed, and an example is given using a case-control sample from a lung cancer study...

Topics

• Case-Control Studies
• Comorbidity
• Confidence Intervals
• Feeding and Eating Disorders
• Female
• Genetic Predisposition to Disease
• Humans
• Logistic Models
• Lung Neoplasms
• Male
• Mood Disorders
• Odds Ratio
• Tobacco Smoke Pollution