Article
Analytical and graphical methods to model the association between family history and disease from a case-control study.
Methods of information in medicine - 1 May 2001
Baglietto L, Severi G, Robertson C, Hopper J L
Abstract excerpt
Subjects within a family have a high probability of sharing environmental factors as well as genes. Without any previous hypothesis, familial aggregation cannot be attributed to genetic or environmental factors. In epidemiology a common measure of familial aggregation is the odds ratio (OR) evaluated from case-control studies which gives a measure of the increased risk associated with particular aspects of the...
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