Article
Analytical and graphical methods to model the association between family history and disease from a case-control study.
Methods of information in medicine - 1 May 2001
Baglietto L, Severi G, Robertson C, Hopper J L
Abstract excerpt
Subjects within a family have a high probability of sharing environmental factors as well as genes. Without any previous hypothesis, familial aggregation cannot be attributed to genetic or environmental factors. In epidemiology a common measure of familial aggregation is the odds ratio (OR) evaluated from case-control studies which gives a measure of the increased risk associated with particular aspects of the...
Topics
- Case-Control Studies
- Colorectal Neoplasms
- Computer Graphics
- Computer Simulation
- Genetic Predisposition to Disease
- Humans
- Mathematical Computing
- Models, Genetic
- Odds Ratio
- Penetrance
- Probability
- Registries
- Risk Assessment
- Social Environment
- Survival Analysis
- Victoria