Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of Transcription Factors AP-1 and NF-κB in Murine Chagasic Myocarditis

18 Apr 2003

Abstract excerpt

The myocardium of CD1 mice was examined for the activation of signal transduction pathways leading to cardiac inflammation and subsequent remodeling during Trypanosoma cruzi infection (Brazil strain). The activity of three pathways of the mitogen-activated protein kinases (MAPKs) was determined. Immunoblotting revealed a persistent elevation of phosphorylated (activated) extracellular-signal-regulated kinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Signaling Pathways in Disease
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12704159
DOI: 10.1128/iai.71.5.2859-2867.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of Transcription Factors AP-1 and NF-κB in Murine Chagasic MyocarditisPMID 12704159Read ↗

Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruziSemantic proximity Read ↗

Gene Expression Changes Associated with Myocarditis and Fibrosis in Hearts of Mice with Chronic Chagasic CardiomyopathySemantic proximity Read ↗

Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infectionSemantic proximity Read ↗

Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.Semantic proximity Read ↗

MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological OutcomesSemantic proximity Read ↗

The effects of inflammation on connexin 43 in chronic Chagas disease cardiomyopathySemantic proximity Read ↗

The absence of myocardial calcium-independent phospholipase A2γ results in impaired prostaglandin E2 production and decreased survival in mice with acute Trypanosoma cruzi infection.Semantic proximity Read ↗

Profiling gene transcription reveals a deficiency of mitochondrial oxidative phosphorylation in Trypanosoma cruzi-infected murine hearts: implications in chagasic myocarditis developmentSemantic proximity Read ↗

Cell-specific Activation of Nuclear Factor-κB by the ParasiteTrypanosoma cruziPromotes Resistance to Intracellular InfectionSemantic proximity Read ↗

DTU I isolates of Trypanosoma cruzi induce upregulation of Galectin-3 in murine myocarditis and fibrosis.Semantic proximity Read ↗

CCR5 Plays a Critical Role in the Development of Myocarditis and Host Protection in Mice Infected withTrypanosoma cruziSemantic proximity Read ↗

Differential susceptibility to acute Trypanosoma cruzi infection in BALB/c and C57BL/6 mice is not associated with a distinct parasite load but cytokine abnormalities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.