Mutation modulating activity in human serum factors induced after parabolic flight.

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Article

Mutation modulating activity in human serum factors induced after parabolic flight.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology - 1 Jul 2000

Takahashi S, Chi X J, Nomura J, Sugaya S, Kita K, Suzuki N

Abstract excerpt

We have reported that human interferon, one of cytokines present in serum, can confer hypomutability on various human cells. On the contrary, we have also reported that serum factors from cancer patients can enhance cell mutability. Therefore, it seems likely that cell mutability is changed by cytokine-like serum factors in our body. It is one of important space problems whether the mutability of human cells is...

Topics

Adult
Endopeptidases
Female
Genes, ras
Humans
Hypergravity
Immunologic Factors
Interferon-alpha
Lymphocytes
Male
Methylnitronitrosoguanidine
Mutagenesis
Mutation
Plasminogen
Space Flight
Weightlessness

Source

Open in PubMed

Identifiers

PMID: 12697563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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