Article
The 4G/4G genotype of the 4G/5G polymorphism of the type-1 plasminogen activator inhibitor (PAI-1) gene is a determinant of penetrating behaviour in patients with Crohn's disease.
Alimentary pharmacology & therapeutics - 1 Apr 2003
Sans M, Tàssies D, Pellisé M, Espinosa G, Quintó L, Piqué J M, Reverter J C, Panés J
Abstract excerpt
BACKGROUND: Crohn's disease is a heterogeneous disorder with polygenic inheritance. AIM: To assess the effect of the 4G/5G polymorphism of the type-1 plasminogen activator inhibitor (PAI-1) gene, the major inhibitor of fibrinolysis, on Crohn's disease susceptibility and phenotype. METHODS: One hu...
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