Article
Analysis of the Fanconi anaemia complementation group A gene in acute myeloid leukaemia.
Leukemia & lymphoma - 1 Sept 2002
Condie Alison, Powles Raymond L, Hudson Chantelle D, Shepherd Valerie, Bevan Stephen, Yuille Martin R, Houlston Richard S
Abstract excerpt
Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults. Around 10-15% of individuals with recessively inherited Fanconi anaemia (FA) develop AML. FA is one of a group of recessive syndromes characterized by excessive spontaneous chromosomal breakage in which heterozygote carriers appear to display an increased risk of cancer and there is some indirect evidence that FA carriers may also be at...
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