Article
Immunofluorometric study of Bcl-2 and Bax expression in clinical fresh tumor samples from breast cancer patients.
Anticancer research - 1 Jan 2000
Martínez-Arribas F, Núñez-Villar M J, Lucas A R, Sánchez J, Tejerina A, Schneider J
Abstract excerpt
BACKGROUND: The balance between the expression of the antiapoptotic gene Bcl-2 and the proapoptotic gene Bax is considered a good indicator of the apoptotic activity of tumor cells. Bcl-2 and Bax expression seem also to individually play a prognostic role in breast cancer. Our aim was to study the expression of both genes in fresh breast cancer samples, and to correlate the obtained results with other available...
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