Article
Associations between genetic polymorphisms of Phase I and II metabolizing enzymes, p53 and susceptibility to esophageal adenocarcinoma.
Cancer detection and prevention - 1 Jan 2003
Casson A G, Zheng Z, Chiasson D, MacDonald K, Riddell D C, Guernsey J R, Guernsey D L, McLaughlin J
Abstract excerpt
The objectives of this exploratory case-control study were to evaluate whether genetic polymorphisms of selected Phase I and II metabolizing enzymes are associated with the risk of developing primary esophageal adenocarcinoma, and to investigate potential associations between genotypes and p53 tumor suppressor gene alterations. Cases comprised 45 patients with surgically resected esophageal adenocarcinomas,...
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