Article
Mutational study of the nuclear factor kappa B inducing kinase gene in patients with progressive supranuclear palsy.
Neuroscience letters - 10 Apr 2003
Campdelacreu Jaume, Ezquerra Mario, Muñoz Esteban, Oliva Rafael, Tolosa Eduardo
Abstract excerpt
The nuclear factor kappa B inducing kinase gene (NIK) is located near the region of the haplotype associated with progressive supranuclear palsy (PSP) in chromosome 17q. We have analysed the coding region of the NIK gene in PSP patients through single strand conformation polymorphism and direct sequencing, in order to investigate the possible existence of pathogenic mutations. A change in exon 15 consisting of a...
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