Article
Detection of methylated ABL1 promoter in philadelphia-negative myeloproliferative disorders.
Blood cells, molecules & diseases - 1 Jan 2000
Aviram Adina, Witenberg Bruria, Shaklai Mati, Blickstein Dorit
Abstract excerpt
Aberrant methylation of tumor-suppressor gene promoter regions may play a causal role in the pre-neoplastic stage of cancer progression. In chronic myeloid leukemia, changes in the methylation status of the CpG-rich islands at several sites in the proximal ABL1 promoter (Pa) on the Philadelphia (...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
