Article
A DNA prime‐live vaccine boost strategy in mice can augment IFN‐γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of <i>Mycobacterium bovis</i> against bovine tuberculosis
1 Apr 2003
Abstract excerpt
The Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine has variable efficacy for both human and bovine tuberculosis. There is a need for improved vaccines or vaccine strategies for control of these diseases. A recently developed prime-boost strategy was investigated for vaccination against M. bovis infection in mice. BALB/c and C57BL/6 mice were primed with a DNA vaccine, expressing two mycobacterial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.