Article
Effect of polymorphism of the endothelial nitric oxide synthase and apolipoprotein E genes on carotid atherosclerosis in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Apr 2003
Asakimori Yukiteru, Yorioka Noriaki, Tanaka Junko, Kohno Nobuoki
Abstract excerpt
BACKGROUND: Decreased synthesis of nitric oxide (NO) and dyslipidemia are implicated in the development of atherosclerosis. METHODS: We investigated the relationship between endothelial NO synthase (eNOS) gene polymorphism, apolipoprotein E (apoE) polymorphism, and carotid atherosclerosis in 163 hemodialysis patients with nondiabetic nephropathy. Intima media thickness of the carotid artery was measured by...
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