Article
Activation of the Human Endogenous Retrovirus W Long Terminal Repeat by Herpes Simplex Virus Type 1 Immediate Early Protein 1
1 Feb 2003
Abstract excerpt
The U3 region of the human endogenous retrovirus W long terminal repeat (HERV-W LTR) contains several putative regulatory sequences that regulate the transcription of neighboring cellular genes, as well as viral genes. We found that the LTR-directed transcription of the HERV-W can be induced by the herpes simplex virus type 1 (HSV-1) infection. The effect was partly mediated by the action of the HSV-1 immediate...
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