Article
Evaluation of the Oculomedin gene in the etiology of primary open angle and exfoliative glaucoma.
Molecular vision - 24 Mar 2003
Jansson Mattias, Tomic Lidija, Larsson Lill-Inger, Wadelius Claes
Abstract excerpt
PURPOSE: Glaucoma is a disease of the retinal ganglion cells leading to reduction of peripheral vision. It is often associated with an increase in intraocular pressure, leading to mechanical stress of tissues. The oculomedin gene is activated by such stretching and is therefore a candidate for causing glaucoma. METHODS: The coding sequence and part of the promoter was screened for sequence variants in Swedish...
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