Polymorphisms of the TAP1 and TAP2 genes in human alveolar echinococcosis.

doi:10.1046/j.1365-2370.2003.00375.x

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Article

Polymorphisms of the TAP1 and TAP2 genes in human alveolar echinococcosis.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2003

Zhang S, Penfornis A, Harraga S, Chabod J, Beurton I, Bresson-Hadni S, Tiberghien P, Kern P, Vuitton D-A

Abstract excerpt

We postulated that TAP genes may influence the susceptibility of some individuals to Echinococcus multilocularis infection. Six coding region variants (codons 333 and 637 in TAP1, and 379, 565, 651 and 665 in TAP2) were typed in 94 patients and 100 controls. Thr/Thr homozygosity at TAP2/665 was more prevalent in patients than in controls [64% vs. 45%, respectively; odds ratio (OR) = 2.1 (95% confidence interval...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Adolescent
Adult
Child
Child, Preschool
Echinococcosis, Hepatic
Female
Genetic Predisposition to Disease
Humans
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 12648282
DOI: 10.1046/j.1365-2370.2003.00375.x

Genes

TAP2
TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.