Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and Structural Characterization of the PezAT Chromosomal Toxin-Antitoxin System of the Human Pathogen Streptococcus pneumoniae

9 May 2007

Abstract excerpt

The chromosomal pezT gene of the Gram-positive pathogen Streptococcus pneumoniae encodes a protein that is homologous to the zeta toxin of the Streptococcus pyogenes plasmid pSM19035-encoded epsilon-zeta toxin-antitoxin system. Overexpression of pezT in Escherichia coli led to severe growth inhibition from which the bacteria recovered approximately 3 h after induction of expression. The toxicity of PezT was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Pneumonia and Respiratory Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17488720
DOI: 10.1074/jbc.m701703200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and Structural Characterization of the PezAT Chromosomal Toxin-Antitoxin System of the Human Pathogen Streptococcus pneumoniaePMID 17488720Read ↗

A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis.Semantic proximity Read ↗

The Streptococcus pneumoniae pezAT Toxin–Antitoxin System Reduces β-Lactam Resistance and Genetic CompetenceSemantic proximity Read ↗

A toxin-antitoxin module as a target for antimicrobial development.Semantic proximity Read ↗

Toxin-Antitoxin Genes of the Gram-Positive Pathogen Streptococcus pneumoniae: So Few and Yet So ManySemantic proximity Read ↗

The Toxin-Antitoxin System of the Streptococcal Plasmid pSM19035Semantic proximity Read ↗

Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operonSemantic proximity Read ↗

Regulatory crosstalk between type I and type II toxin-antitoxin systems in the human pathogen Enterococcus faecalisSemantic proximity Read ↗

Toxin-Antitoxin Systems of Staphylococcus aureusSemantic proximity Read ↗

The chromosomal mazEF locus of Streptococcus mutans encodes a functional type II toxin-antitoxin addiction system.Semantic proximity Read ↗

Toxinome - The Bacterial Protein Toxin DatabaseSemantic proximity Read ↗

Axe–Txe, a broad‐spectrum proteic toxin–antitoxin system specified by a multidrug‐resistant, clinical isolate of <i>Enterococcus faecium</i>Semantic proximity Read ↗

Type II Toxin-Antitoxin Systems: Evolution and Revolutions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.