Article
Association of HLA-DR and type II collagen autoimmunity with Meniere's disease.
Tissue antigens - 1 Jan 2003
Koo J-W, Oh S H, Chang S O, Park M H, Lim M J, Yoo T-J, Kim C S
Abstract excerpt
To investigate HLA-associated genetic susceptibility to Meniere's disease in relation to type II collagen (CII) autoimmunity status, HLA-DRB1 genotyping and ELISA measurement of anti-CII antibody were performed in 41 Korean patients with Meniere's disease. In the anti-CII positive subgroup (20%) of patients, the frequency of HLA-DRB1*0405 was significantly increased (uncorrected) compared with both controls (63%...
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