Article
HLA class I polymorphisms in Tunisian patients with otosclerosis.
Annals of human biology - 1 May 2012
Bel Hadj Ali Insaf, Ben Saida Asma, Beltaief Najeh, Namouchi Imen, Besbes Ghazi, Ghazoueni Ezzeddine, Ben Arab Saida
Abstract excerpt
BACKGROUND: Otosclerosis is a common form of hearing impairment among Western-Eurasian adults. The cause of otosclerosis remains unknown. Autoimmune reaction against the otic capsule has been suggested as a possible aetiologic factor in otosclerosis. AIM: The present study is the first report to evaluate the relationship between class I major histocompatibility complex (MHC) genes (HLA-A, HLA-B and HLA-Cw) and...
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