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Article

The genetic basis of pulmonary arterial hypertension.

Human genetics - 1 May 2014

Ma Lijiang, Chung Wendy K

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a rare disease characterized by distinctive changes in pulmonary arterioles that lead to progressive elevation of pulmonary artery pressure, pulmonary vascular resistance, right ventricular failure, and a high mortality rate. The etiology of PAH is heterogeneous and incompletely understood. Based on clinical classification, WHO Group 1 PAH includes sporadic disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24442418
DOI: 10.1007/s00439-014-1419-3

Genes

PAH
CAV1
KCNK3
ALK
BMPR2
CBLN2
ENG
SMAD2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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