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Article

The crystal structure and stereospecificity of levodione reductase from Corynebacterium aquaticum M-13.

The Journal of biological chemistry - 23 May 2003

Sogabe Satoshi, Yoshizumi Ayumi, Fukami Takaaki A, Shiratori Yasuhiko, Shimizu Sakayu, Takagi Hiroshi, Nakamori Shigeru, Wada Masaru

Abstract excerpt

The (6R)-2,2,6-trimethyl-1,4-cyclohexanedione (levodione) reductase (LVR) of the soil isolate bacterium Corynebacterium aquaticum M-13 is a NAD(H)-linked enzyme that catalyzes reversible oxidoreduction between (4R)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone (actinol) and levodione. Here the crystal structure of a ternary complex of LVR with NADH and its inhibitor 2-methyl-2,4-pentanediol has been determined by...

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PMID: 12621044
DOI: 10.1074/jbc.M208146200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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