Article
Putative homologs of SSK22 MAPKK kinase and PBS2 MAPK kinase of Saccharomyces cerevisiae encoded by os-4 and os-5 genes for osmotic sensitivity and fungicide resistance in Neurospora crassa.
Bioscience, biotechnology, and biochemistry - 1 Jan 2003
Fujimura Makoto, Ochiai Noriyuki, Oshima Michiyo, Motoyama Takayuki, Ichiishi Akihiko, Usami Ron, Horikoshi Koki, Yamaguchi Isamu
Abstract excerpt
We cloned and characterized Neurospora NcSSK22 and NcPBS2 genes, similar to yeast SSK22 mitogen-activated protein (MAP) kinase kinase kinase and the PBS2 MAP kinase kinase genes, respectively. Disruptants of the NcSSK22 gene were sensitive to osmotic stress and resistant to iprodione and fludioxo...
Topics
- Amino Acid Sequence
- Aminoimidazole Carboxamide
- Cloning, Molecular
- Databases, Genetic
- Dioxoles
- Drug Resistance, Fungal
- Fungicides, Industrial
- Genes, Fungal
- Genome, Fungal
- Hydantoins
- MAP Kinase Kinase Kinases
- Mitogen-Activated Protein Kinase Kinases