Article
Human ABO blood group is important in survival and function of porcine working hearts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Mar 2003
Manji Rizwan A, Manji Jacqueline S, Koshal Arvind, Korbutt Gregory S, Rajotte Ray V
Abstract excerpt
Pig organs express alphaGal antigen and thus are hyperacutely rejected if perfused by human blood. Human B/A antigens are similar to pig alphaGal antigen, suggesting that the corresponding antibodies may cross-react. Our purpose was to determine if there is a human ABO blood-group difference in porcine-human xenotransplantation. Plasma from six A, five B, seven AB, and six O individuals pooled by blood group were...
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