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Article

The methylentetrahydrofolate reductase C677T point mutation is a risk factor for vascular access thrombosis in hemodialysis patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 2003

Fukasawa Mizuya, Matsushita Kazumichi, Kamiyama Manabu, Mikami Yuki, Araki Isao, Yamagata Zentaro, Takeda Masayuki

Abstract excerpt

BACKGROUND: Many reports indicate that a high homocysteine (Hcy) level is a potential risk factor for such thrombotic diseases as arteriosclerosis, myocardial infarction, and cerebral infarction in healthy individuals or hemodialysis (HD) patients. The methylentetrahydrofolate reductase (MTHFR) C677T polymorphism has been reported to be closely related to plasma Hcy level. METHODS: Using a cross-sectional design...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Oxidoreductases Acting on CH-NH Group Donors

Share to Renal Dialysis

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Source

Identifiers

PMID: 12612987
DOI: 10.1053/ajkd.2003.50125

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The methylentetrahydrofolate reductase C677T point mutation is a risk factor for vascular access thrombosis in hemodialysis patients.PMID 12612987Read ↗

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