Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis.

The Journal of rheumatology - 1 Mar 2003

Fedetz Maria, Matesanz Fuencisla, Cáliz Rafael, Ferrer Miguel Angel, Collado Maria Dolores, Alcina Antonio, Martín Javier

Abstract excerpt

OBJECTIVE: To investigate the association of 2 single nucleotide polymorphisms (SNP) at positions -384 and 114 in the human interleukin 2 (IL-2) gene with susceptibility to and severity of rheumatoid arthritis (RA). METHODS: Genotyping for these IL-2 variants was performed by a polymerase chain reaction restriction fragment length polymorphism method in 174 RA patients and 153 control individuals. RESULTS: No...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Interleukin-2

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Severity of Illness Index

Source

Identifiers

PMID: 12610796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis.PMID 12610796Read ↗

No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis.Semantic proximity Read ↗

Lack of association of IL-2RA and IL-2RB polymorphisms with rheumatoid arthritis in a Han Chinese population.Semantic proximity Read ↗

Interleukin-18 gene polymorphism, but not interleukin-2 gene polymorphism, is associated with rheumatoid arthritis.Semantic proximity Read ↗

An assessment of the association between IL-2 gene polymorphisms and Japanese patients with multiple sclerosis.Semantic proximity Read ↗

Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid arthritis.Semantic proximity Read ↗

A single nucleotide polymorphism in exon 1 of cytotoxic T-lymphocyte-associated-4 (CTLA-4) is not associated with rheumatoid arthritis.Semantic proximity Read ↗

Interleukin-2 receptor beta (IL-2R beta)-627*C homozygote but not IL-12R beta 1 codon 378 or IL-18 105 polymorphism is associated with higher susceptibility to endometriosis.Semantic proximity Read ↗

Involvement of Fcgamma receptor IIIA genotypes in susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Allelic expression and interleukin-2 polymorphisms in multiple sclerosis.Semantic proximity Read ↗

No association between tumour necrosis factor receptor type 2 gene polymorphism and rheumatoid arthritis severity: a comparison of the extremes of phenotypes.Semantic proximity Read ↗

Analysis of IL-12 p40 subunit gene and IFN-gamma G5644A polymorphisms in Idiopathic Pulmonary Fibrosis.Semantic proximity Read ↗

Susceptibility to rheumatoid arthritis is not associated with a single common allele of the type 2 collagen gene (COL2A1)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.