Article
[Significance of tumor necrosis factor-alpha gene polymorphism in patients with acute severe pancreatitis].
Zhonghua yi xue za zhi - 25 Nov 2002
Zhang Dianliang, Li Jieshou, Jiang Zhiwei, Yu Baojun, Tang Xingming
Abstract excerpt
OBJECTIVE: To investigate the relation of the frequency of TNF2 allele, a TNF-alpha promoter polymorphism, and plasma concentrations of TNF-alpha and soluble tumor necrosis receptor (sTNF-R) to acute severe pancreatitis (ASP) and its severe complication--sepsis. METHODS: The DNA samples of peripheral white blood cells of 72 ASP patients, 16 of them being complicated by severe sepsis and the other 46 cases being...
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