Article
Viral kinetics and early prediction of nonresponse to peg-IFN-alpha-2b plus ribavirin in HCV genotypes 1/4 according to HIV serostatus.
Journal of viral hepatitis - 1 Jul 2006
Moreno A, Bárcena R, García-Garzón S, Moreno L, Quereda C, Muriel A, Zamora J, Mateos M L, Pérez-Elías M J, Antela A, Diz S, Moreno A, Moreno S
Abstract excerpt
To evaluate, among 70 hepatitis C virus (HCV)-monoinfected and 36 human immunodeficiency virus (HIV)-coinfected naïve patients with genotypes 1/4 receiving weight-adjusted pegylated interferon-alpha-2b/ribavirin, viral kinetics and the feasibility to predict treatment failure measuring early HCV-RNA decreases. HCV-RNA was assessed at baseline, weeks 4, 12 and 24. Receiver operating characteristic (ROC) curves...
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