Article
Activation of the Drosophila TRP and TRPL channels requires both Ca2+ and protein dephosphorylation.
Cell calcium - 1 Feb 2004
Agam Keren, Frechter Shahar, Minke Baruch
Abstract excerpt
The Transient Receptor Potential (TRP) proteins constitute a large and diverse family of channel proteins, which is conserved through evolution. TRP channel proteins have critical functions in many tissues and cell types, but their gating mechanism is an enigma. In the present study patch-clamp whole-cell recordings was applied to measure the TRP- and TRP-like (TRPL)-dependent currents in isolated Drosophila...
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