Article
The Synaptonemal complex component C(2)M regulates meiotic crossing over in Drosophila.
Current biology : CB - 18 Feb 2003
Manheim Elizabeth A, McKim Kim S
Abstract excerpt
BACKGROUND: The synaptonemal complex (SC) is a proteinaceous structure that forms between homologously paired meiotic chromosomes. Previous studies have suggested that the SC is required for meiotic crossing over in Drosophila. However, only one component of this structure, C(3)G, has been identified in Drosophila. RESULTS: Mutations in c(2)M cause a reduced frequency of meiotic crossing over due, in part, to how...
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