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Article

Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men.

Journal of vascular surgery - 1 Aug 2013

Wong Yuen Y E, Golledge Jonathan, Flicker Leon, McCaul Kieran A, Hankey Graeme J, van Bockxmeer Frank M, Yeap Bu B, Norman Paul E

Abstract excerpt

OBJECTIVE: This study was conducted to determine whether plasma total homocysteine (tHcy) and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism are associated with abdominal aortic aneurysm (AAA) and aortic diameter. METHODS: This was a cross-sectional study set in Western Austra...

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Source

Identifiers

PMID: 23643559
DOI: 10.1016/j.jvs.2013.01.046

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23643559-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

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Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men.PMID 23643559Read ↗

Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk: A comprehensive meta-analysis with 10,123 participants involved.Semantic proximity Read ↗

Associations of global DNA methylation and homocysteine levels with abdominal aortic aneurysm: A cohort study from a population-based screening program in SwedenSemantic proximity Read ↗

The methylenetetrahydrofolate reductase C677T polymorphism does not associate with susceptibility to abdominal aortic aneurysm.Semantic proximity Read ↗

Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han populationSemantic proximity Read ↗

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Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T allele.Semantic proximity Read ↗

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation.Semantic proximity Read ↗

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High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysmSemantic proximity Read ↗

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[The normotensive carriers of the MTHFR 677T allele, displaying the increased risk of development of the abdominal aortic aneurysm (AAA), occur at the highest frequency among the smoking patients].Semantic proximity Read ↗

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